1.
Front Endocrinol (Lausanne)
; 11: 585922, 2020.
Article
in English
| MEDLINE | ID: covidwho-1389157
Subject(s)
Coronavirus Infections , Organoids , Pandemics , Pluripotent Stem Cells , Pneumonia, Viral , Betacoronavirus , COVID-19 , Humans , SARS-CoV-2 , Tropism
2.
Trends Endocrinol Metab
; 32(11): 842-845, 2021 11.
Article
in English
| MEDLINE | ID: covidwho-1349597
ABSTRACT
The widespread extrapulmonary complications of coronavirus disease 2019 (COVID-19) have gained momentum; the pancreas is another major target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we take a closer look into potential pathological interactions. We provide an overview of the current knowledge and understanding of SARS-CoV-2 infection of the pancreas with a special focus on pancreatic islets and propose direct, indirect, and systemic mechanisms for pancreas injury as result of the COVID-19-diabetes fatal bidirectional relationship.
Subject(s)
COVID-19/metabolism , Diabetes Mellitus/metabolism , Insulin-Secreting Cells/metabolism , Acinar Cells/metabolism , Angiotensin-Converting Enzyme 2/metabolism , Glucagon-Secreting Cells/metabolism , Humans , Islets of Langerhans/metabolism , Pancreas/metabolism , Receptors, Coronavirus/metabolism , SARS-CoV-2/metabolism , Serine Endopeptidases/metabolism , Viral Tropism
3.
Signal Transduct Target Ther
; 6(1): 112, 2021 03 06.
Article
in English
| MEDLINE | ID: covidwho-1118800